Electron Microscope Observations on the Endoplasmic Reticulum in the Human Fetal Adrenal

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Abstract
A study of the fine structure of fetal zone cells has shown a very extensive, densely packed system of tubules which occupies most of the cytoplasm and are considered to be morphologically homologous to the agranular endoplasmic reticulum found in other cells. The endoplasmic reticulum of the fetal zone differs from most other cell types in that it is predominantly made up of tortuous tubules of slightly irregular diameter (250-300 A ). It is suggested that this smooth surfaced membrane system with no attached ribonucleoprotein particles can be correlated with the high steroid biogenetic capacity of fetal zone cells.

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