Effect of Some Sulfhydryl-containing Substances on the Toxicity of an Organic Mercurial Compound
- 6 September 1946
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 104 (2697) , 220-221
- https://doi.org/10.1126/science.104.2697.220
Abstract
The acute toxicity of an organic mercurial as studied on the mouse, intact anesthetized cat and dog, and the heart-lung preparation of the dog can be readily counteracted by sulfhydryl-containing compounds such as glutathione, cysteine, and 2,3-dimercapto-propanol. Equimolar doses of 2,3-dimercapto-propanol are about five times as active as cysteine or glutathione.Keywords
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