IMMUNE-RESPONSE OF RABBITS TO 3 STRAINS OF MYCOPLASMA-AGALACTIAE VAR BOVIS ISOLATED FROM MASTITIC BOVINE UDDERS

  • 1 January 1976
    • journal article
    • research article
    • Vol. 66  (2) , 143-151
Abstract
Rabbits were given 3 serologically-related strains of Mycoplasma isolated from mastitic bovine udders. Growth inhibiting antibodies were not found. High-titered sera from each rabbit immunized with each strain developed at least 4 precipitin lines to each organism, and at least 1 line of identity was demonstrated between the organisms. Significant indirect hemagglutination titers were found in all rabbits in 1 wk, with titers reaching 1.0 .times. 105-3.3 .times. 105 in 4-6 wk, but despite continued i.v. antigenic stimulation, titers quickly fell to low levels thereafter.