THE SPECIFICITY OF ALLERGIC REACTIONS

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Abstract
Guinea pigs sensitized with either hen, duck, or goose egg albumin showed delayed hypersensitivity followed by Arthus reactions to the homologous antigen, but tended to have much weaker delayed responses and slower antibody formation to heterologous antigens. Guinea pigs with delayed hypersensitivity to one of the avian antigens had a slower antibody response to a secondary injection of heterologous antigen than to one of the homologous antigen.