Immunogenicity of fully defined lysine LAG dodecapeptides in guinea-pigs: with a note on an antigenic cooperation effect in the delayed immune response.

  • 1 December 1972
    • journal article
    • Vol. 23  (6) , 911-20
Abstract
The immunogenicity of a series of dodecapeptides was evaluated in random-bred guinea-pigs. The peptides were synthesized by an economical two-phase approach specifically developed for the production of gram-amounts of peptide antigens. The peptides contain L-leucine, L-alanine, glycine and L-lysine and differ from each other by number and distribution of lysine residues. Some of the peptides carry DNP groups at their N-terminus.