PHARMACOLOGICAL PROPERTIES OF NANDROLONE DECANOATE
- 1 November 1960
- journal article
- research article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. XXXV (III) , 405-412
- https://doi.org/10.1530/acta.0.xxxv0405
Abstract
1. The pharmacological properties of nandrolone decanoate (= caprinate), by abbreviation nor-A. D., have been studied. 2. Nor-A. D. has a marked, long-lasting effect on the levator ani muscle of the castrated rat, but it has little activity on the seminal vesicles and prostate. 3. Nor-A. D. displays only weak gonad inhibiting properties in male and female rats. 4. The anti-oestrogenic activity is low. 5. At high dose levels the anabolic activity becomes maximal and the other effects become evident. The same can be expected to occur if injections are administered with too great a frequency. 6. Chronic toxicity studies in rats and dogs demonstrate its lack of toxicity.Keywords
This publication has 2 references indexed in Scilit:
- NOR-ANDROSTENOLONEPHENYLPROPIONATE, A NEW POTENT ANABOLIC ESTERActa Endocrinologica, 1957
- Myotrophic Activity of 19-Nortestosterone and Other Steroids Determined by Modified Levator Ani Muscle Method.Experimental Biology and Medicine, 1953