Complement-Fixing Antigens of Living and Inactivated Poliovirus. II. Complement-Fixing Activity of Poliomyelitis Vaccine and Its Relation to Immunogenic Potency

Abstract
After concentration, sufficient antigen is present in most vaccines to react with potent guinea pig anti-poliovirus sera. There appears to be a rough relationship between antigen titer and a vaccine''s immunogenic potency for the monkey.