Synthesis and properties of novel pyrazolopyrimidine derivatives containing sulfur atom
- 1 January 2004
- journal article
- research article
- Published by Wiley in Heteroatom Chemistry
- Vol. 15 (4) , 333-337
- https://doi.org/10.1002/hc.20024
Abstract
A series of new pyrazolopyrimidine derivatives containing sulfur atom 5 has been designed and synthesized by treatment of carbodiimide 3, which came from iminophosphorane 2 undergoing a aza‐Wittig reaction with phenyl ioscyanate, with alkylamine. The structures of compounds 5 were confirmed by 1H NMR, IR, EI‐mass spectroscopy, and elemental analysis. The results of preliminary bioassay indicate that most compounds 5 exhibit an inhibition effect against Cercospora beticola, Botryosphaeria berengeriana, and Pellicularia sasakii, and compound 5g shows 91.2% inhibitory rate to root of rape and the other less than 50% at 100 mg/l. © 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:333–337, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20024Keywords
This publication has 12 references indexed in Scilit:
- Synthesis and in vitro antifungal activity of 1‐amino‐3,4‐dialkylnaphthalene‐2‐carbonitriles and their analoguesPest Management Science, 2001
- Synthesis and bioactivity of novel triazolo [1,5‐a]pyrimidine derivatives[3]Heteroatom Chemistry, 2001
- A Facile Synthesis of 2-Mino-3H-Quinazolin-4-Ones with Tandem Aza-Wittig ReactionSynthetic Communications, 2000
- New Facile Synthesis of 2-Aryloxy-4H-Imidazolin-4-Ones Via Base Catalytic Reactions of Phenols with Functionalized CarbodiimidesSynthetic Communications, 1999
- Methyl 3-(triphenylphosphoranylideneamino)pyrazine-2-carboxylate: synthesis, crystal structure and use in pteridin-4(3H)ones synthesisJournal of the Chemical Society, Perkin Transactions 1, 1996
- On the Synthesis of Zwitterionic Heteropolycyclic Pyrazoles by a Three-Component Reaction. Some Mechanistic ConsiderationsThe Journal of Organic Chemistry, 1994
- A simple aza wittig‐mediated pyrimidine annulation reactionJournal of Heterocyclic Chemistry, 1991
- Synthesis of pyrazolo[3,4‐d]pyrimidine derivatives using ketene dithioacetalsJournal of Heterocyclic Chemistry, 1990
- Ketenderivate, III. Pyrazole und Isoxazole aus KetenmercaptalenEuropean Journal of Inorganic Chemistry, 1962
- The Synthesis and Properties of 6-Chloropurine and Purine1Journal of the American Chemical Society, 1954