Group sequential designs using a family of type I error probability spending functions
- 1 December 1990
- journal article
- research article
- Published by Wiley in Statistics in Medicine
- Vol. 9 (12) , 1439-1445
- https://doi.org/10.1002/sim.4780091207
Abstract
Performing planned or unplanned interim analyses on accumulating data in clinical trials is a frequent practice. In this paper, we propose a general one‐parameter family of type I error probability spending functions to construct customized group sequential boundaries with unequal increments in information time. This proposed family generalizes the spending functions of Lan and DeMets1 and Kim and DeMets.2 We give an example to illustrate the use of this family.This publication has 14 references indexed in Scilit:
- Group sequential procedures: Calendar versus information timeStatistics in Medicine, 1989
- Design and analysis of group sequential tests based on the type I error spending rate functionBiometrika, 1987
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- Discrete Sequential Boundaries for Clinical TrialsBiometrika, 1983
- Two-Sample Repeated Significance Tests Based on the Modified Wilcoxon StatisticJournal of the American Statistical Association, 1982
- Group sequential methods in the design and analysis of clinical trialsBiometrika, 1977