Antisense technologies
Top Cited Papers
Open Access
- 26 March 2003
- journal article
- review article
- Published by Wiley in European Journal of Biochemistry
- Vol. 270 (8) , 1628-1644
- https://doi.org/10.1046/j.1432-1033.2003.03555.x
Abstract
Antisense agents are valuable tools to inhibit the expression of a target gene in a sequence‐specific manner, and may be used for functional genomics, target validation and therapeutic purposes. Thre...Keywords
This publication has 122 references indexed in Scilit:
- RNA interferenceNature, 2002
- Discovery and Development of Respirable Antisense Therapeutics for AsthmaAntisense and Nucleic Acid Drug Development, 2002
- Effective expression of small interfering RNA in human cellsNature Biotechnology, 2002
- U6 promoter–driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cellsNature Biotechnology, 2002
- Comparative Study of DNA Enzymes and Ribozymes against the Same Full-length Messenger RNA of the Vanilloid Receptor Subtype IJournal of Biological Chemistry, 2002
- Potent Gene-Specific Inhibitory Properties of Mixed-Backbone Antisense Oligonucleotides Comprised of 2‘-Deoxy-2‘-fluoro-d-arabinose and 2‘-Deoxyribose Nucleotides,Biochemistry, 2002
- Antisense therapy in oncology: new hope for an old idea?The Lancet, 2001
- Effective targeted gene ‘knockdown’ in zebrafishNature Genetics, 2000
- Tetranucleotide GGGA Motif in Primary RNA TranscriptsPublished by Elsevier ,1998
- Sequence-Selective Recognition of DNA by Strand Displacement with a Thymine-Substituted PolyamideScience, 1991