Role of heterotrimeric GTP binding proteins in vesicular protein transport: indications for both classical and alternative G protein cycles
- 1 August 1995
- journal article
- review article
- Published by Wiley in FEBS Letters
- Vol. 369 (1) , 84-88
- https://doi.org/10.1016/0014-5793(95)00620-o
Abstract
Heterotrimeric G proteins are involved in hormonal signal transduction across the plasma membrane. Recent evidence suggests that they have a role in vesicular protein transport as well. Biochemical probes that interfere with the classical G protein cycle have been applied to the field of intracellular membrane transport to study their mechanism of action. Evidence has been obtained that intracellular G proteins act both through classical and alternative G protein cycles.Keywords
This publication has 76 references indexed in Scilit:
- The small G‐protein ARF1GDP binds to the Gtβγ subunit of transducin, but not to GtαGDP‐GtβγFEBS Letters, 1995
- GTPase mechanism of Gproteins from the 1.7-Å crystal structure of transducin α - GDP AIF−4Nature, 1994
- Mechanisms of intracellular protein transportNature, 1994
- The ancient regulatory-protein family of WD-repeat proteinsNature, 1994
- Cellular variations in heterotrimeric G protein localization and expression in rat pituitaryEndocrinology, 1994
- Evidence of a Role for Heterotrimeric GTP-Binding Proteins in Endosome FusionScience, 1992
- Trimeric G‐proteins of the trans‐Golgi network are involved in the formation of constitutive secretory vesicles and immature secretory granulesFEBS Letters, 1991
- Aluminofluoride and beryllofluoride complexes: new phosphate analogs in enzymologyTrends in Biochemical Sciences, 1990
- Demonstration of the presence of G-proteins in hepatic microsomal fractionBiochemical and Biophysical Research Communications, 1988
- Presence of three pertussis toxin substrates and Goα immunoreactivity in both plasma and granule membranes of chromaffin cellsFEBS Letters, 1987