Histopathological method for diagnosis of cryptosporidiosis using monoclonal antibodies
- 1 September 1990
- journal article
- research article
- Published by Springer Nature in European Journal of Clinical Microbiology & Infectious Diseases
- Vol. 9 (9) , 664-666
- https://doi.org/10.1007/bf01964268
Abstract
A monoclonal antibody directed against the oocyst wall ofCryptosporidium parvum was produced which strongly reacted with 25 strains of the parasite. This antibody was assessed for use in a diagnostic immunoperoxidase assay performed on tissue sections. It permitted an intense and specific staining of the parasite in five biopsies positive forCryptosporidium parvum fixed with routine techniques. The procedure described may be useful in screening mucosal biopsies from immunosuppressed patients.Keywords
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