Species-Specific Differences in the Susceptibilities of Biofilms Formed by Candida Bloodstream Isolates to Echinocandin Antifungals
- 1 April 2007
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 51 (4) , 1520-1523
- https://doi.org/10.1128/aac.01141-06
Abstract
The echinocandin susceptibilities of bloodstream Candida isolates growing in a biofilm was investigated. Within the therapeutic range of concentrations of each drug, caspofungin and micafungin were active against biofilms formed by Candida albicans or C. glabrata but not those formed by C. tropicalis or C. parapsilosis.Keywords
This publication has 16 references indexed in Scilit:
- Candida biofilms: antifungal resistance and emerging therapeutic options.2004
- In vitro activities of voriconazole, posaconazole, and fluconazole against 4,169 clinical isolates of Candida spp. and Cryptococcus neoformans collected during 2001 and 2002 in the ARTEMIS global antifungal surveillance programDiagnostic Microbiology and Infectious Disease, 2004
- In Vitro Pharmacodynamic Properties of Three Antifungal Agents against PreformedCandida albicansBiofilms Determined by Time-Kill StudiesAntimicrobial Agents and Chemotherapy, 2002
- In Vitro Activity of Caspofungin against Candida albicans BiofilmsAntimicrobial Agents and Chemotherapy, 2002
- Antifungal Activity of Amphotericin B, Fluconazole, and Voriconazole in an In Vitro Model of Candida Catheter-Related Bloodstream InfectionAntimicrobial Agents and Chemotherapy, 2002
- Antifungal Susceptibility ofCandidaBiofilms: Unique Efficacy of Amphotericin B Lipid Formulations and EchinocandinsAntimicrobial Agents and Chemotherapy, 2002
- Biofilm Production by Isolates of Candida Species Recovered from Nonneutropenic Patients: Comparison of Bloodstream Isolates with Isolates from Other SourcesJournal of Clinical Microbiology, 2002
- Comparison of Biofilms Formed byCandidaalbicansandCandidaparapsilosison Bioprosthetic SurfacesInfection and Immunity, 2002
- Standardized Method for In Vitro Antifungal Susceptibility Testing of Candida albicans BiofilmsAntimicrobial Agents and Chemotherapy, 2001
- Risk Factors for Candidal Bloodstream Infections in Surgical Intensive Care Unit Patients: The NEMIS Prospective Multicenter StudyClinical Infectious Diseases, 2001