Evaluation of Several Geometric Models for Estimation of Left Ventricular Circumferential Wall Stress
- 1 September 1973
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation Research
- Vol. 33 (3) , 303-312
- https://doi.org/10.1161/01.res.33.3.303
Abstract
Phasic left ventricular wall force and wall thickness were monitored with appropriate transducers to provide a direct measurement of circumferential wall stress in open-chest dogs. Left ventricular pressure and measurements of chamber geometry were used to estimate the wall stress using several geometric models. During the initial control period, peak and end-ejection measured wall stresses were 207 ± 19 and 104 ± 13 g/cm2, respectively. The best estimates of these values were 198 ± 18 and 117 ± 11 g/cm2 obtained from a modified thin-wall ellipse formula in which the midwall rather than the endocardial radius was used. Wide variations in hemodynamic conditions were produced with intravenous infusions of nitroglycerin, phenylephrine, and isoproterenol. Comparison of directly measured and estimated values during all control periods and during the response to these interventions showed that both the modified thin-wall ellipse and a thick-wall ellipse were generally accurate predictors of the measured wall stress. All other models tended to underestimate measured stress. The sensitivity of the estimated wall stress computed by the models to geometric measurement errors was also evaluated. A thick-wall sphere was the most sensitive to both circumferential length and wall thickness measurement errors, and a thick-wall ellipse was the least sensitive. All models examined were relatively insensitive to base-to-apex length measurement errors.Keywords
This publication has 16 references indexed in Scilit:
- An improved transducer to measure left ventricular wall thickness in open-chest dogsJournal of Applied Physiology, 1972
- Direct measurement of tension within left ventricular wall of the dog heartCardiovascular Research, 1972
- Comparison of Directly Measured Left Ventricular Wall Stress and Stress Calculated from Geometric Reference FiguresCirculation Research, 1971
- Stress Distribution in the Canine Left Ventricle during Diastole and SystoleBiophysical Journal, 1970
- Left Ventricular Wall Stress Calculated from One-Plane CineangiographyCirculation Research, 1970
- Production of isotonic contractions in the intact canine left ventricle.Journal of Applied Physiology, 1969
- An analytic elastic-viscoelastic model for the shape and the forces in the left ventricleJournal of Biomechanics, 1969
- Left Ventricular Stresses in the Intact Human HeartBiophysical Journal, 1969
- Stress distribution within the left ventricular wall approximated as a thick ellipsoidal shellAmerican Heart Journal, 1968
- Auxotonic and isometric cardiac force transducers.Journal of Applied Physiology, 1967