The Production of Nitrite from Radiolytic, Photolytic and Electrolytic Degradation of Metronidazole
- 1 January 1982
- journal article
- research article
- Published by Taylor & Francis in International Journal of Radiation Biology
- Vol. 42 (1) , 105-109
- https://doi.org/10.1080/09553008214550961
Abstract
The results obtained by UV-and .gamma.-irradiation and electrolysis of metronidazol (a hypoxic cell radiosensitizer) in aqueous media were reported. An alternative route, involving the production of nitrite ions, is available for the reduction mechanism of metronidazole.This publication has 9 references indexed in Scilit:
- The interaction of reduced metronidazole with DNABiochemical Pharmacology, 1978
- Oxidation of hydroxylamine to nitrite as an assay for the combined presence of superoxide anions and hydroxyl radicalsBiochemical and Biophysical Research Communications, 1977
- Electron-Affinic Sensitization: VI. A Pulse Radiolysis and ESR Comparison of Some 2- and 5-NitroimidazolesRadiation Research, 1975
- Photochemistry of the nitro group in aromatic heterocyclic moleculesThe Journal of Physical Chemistry, 1975
- Metronidazole (‘Flagyl’): Mechanisms of RadiosensitizationInternational Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, 1974
- Radiosensitization of anoxic cells by metronidazoleThe British Journal of Radiology, 1973
- Rates of decomposition of nitro radical anionsJournal of the American Chemical Society, 1968
- Photochemical studies. VI. Photochemistry of nitrobenzoate esters and related nitroaromatic compounds. Some novel reduction and esterification reactionsJournal of the American Chemical Society, 1968
- Cleavage Reactions of Tertiary Nitro Anion RadicalsJournal of the American Chemical Society, 1964