Yb‐DTPA, a novel contrast agent in magnetic resonance imaging: Application to rat kidney
- 1 February 1991
- journal article
- Published by Wiley in Magnetic Resonance in Medicine
- Vol. 17 (2) , 328-335
- https://doi.org/10.1002/mrm.1910170205
Abstract
We have developed a novel contrast agent, ytterbium‐diethylenetriamine pentaacetic acid (Yb‐DTPA), for magnetic resonance imaging (MRI) and its mechanism of action is predominantly by the susceptibility mechanism. We have applied this contrast agent for renal MRI studies. We also demonstrate that Yb‐DTPA has a renal clearance similar to that of inulin in rats and may therefore be useful for the estimation of glomerular filtration rate. © 1991 Academic Press, Inc.Keywords
This publication has 10 references indexed in Scilit:
- Use of Gd-DTPA and fast gradient-echo and spin-echo MR imaging to demonstrate renal function in the rabbit.Radiology, 1989
- Renal imaging studies at 1.5 and 9.4 T: Effects of diureticsMagnetic Resonance in Medicine, 1988
- Dynamic imaging with lanthanide chelates in normal brain: Contrast due to magnetic susceptibility effectsMagnetic Resonance in Medicine, 1988
- Relaxation of solvent protons by paramagnetic ions and its dependence on magnetic field and chemical environment: implications for NMR imagingMagnetic Resonance in Medicine, 1984
- Determination of metal chelates by inductively coupled plasma atomic emission spectrometry and applications to biological materialsAnalytical Chemistry, 1981
- An inexpensive, high output voltage, voltage clamp for epithelial membranesAmerican Journal of Physiology-Cell Physiology, 1978
- Measurement of Glomerular Filtration Rate using a Single Injection of 51Cr‐Edetic AcidAustralasian Annals of Medicine, 1970
- Indium-113m Diethylenetriaminepentaacetic Acid (DTPA): A New Radiopharmaceutical for Study of the KidneysRadiology, 1968
- A new method for the determination of inulin in plasma and urineClinica Chimica Acta; International Journal of Clinical Chemistry, 1956
- The separation of the lanthanons with the aid of ethylenediaminetetra-acetic acid (“enta acid”). Part V. The solubilities of some alkali lanthanon enta saltsJournal of the Chemical Society, 1955