Inhibition of chitin synthesis in an insect cell‐line
- 1 January 1989
- journal article
- research article
- Published by Wiley in Pesticide Science
- Vol. 25 (2) , 115-121
- https://doi.org/10.1002/ps.2780250203
Abstract
An epithelial cell‐line from Chironomus tentans, able to synthesise chitin in considerable amounts, was used as a test system to study the influence of tunicamycin (I20=750 nM), the benzoylphenylurea derivative SIR 8514 (I50=100 nM), oligomycin (I50=200 nM), avermectin (I50=5 μM) and nikkomycin Z (I50,=50 μM) on the rate of glucosamine incorporation into chitin. Chitin synthesis was diminished by application of 20‐hydroxyecdysone.Keywords
This publication has 23 references indexed in Scilit:
- Ecdysteroid production by a continuous insect cell lineArchives of Insect Biochemistry and Physiology, 1987
- Ivermectin: Fleas, fungi and pharmacologyParasitology Today, 1986
- Effects of diflubenzuron and tunicamycin on N-acetylglucosaminyl transferases in prepupae of the stable fly (Stomoxys calcitrans)Cellular and Molecular Life Sciences, 1985
- Mode of Inhibition of Chitin Synthesis by Diflubenzuron in the Cabbage Armyworm, Mamestra brassicae L.Journal of Pesticide Science, 1984
- Evidence for chitin synthesis in an insect cell lineArchives of Insect Biochemistry and Physiology, 1983
- Chitin synthesis inhibiting insect growth regulators do not inhibit chitin synthaseCellular and Molecular Life Sciences, 1981
- Inhibition of Cellular Proliferation of Imaginal Epidermal Cells by Diflubenzuron in Pupae of the Stable FlyScience, 1980
- Inhibition of chitin biosynthesis in cultured imaginal discs: Effects of alpha-amanitin, actinomycin-D, cycloheximide, and puromycinWilhelm Roux' Archiv für Entwicklungsmechanik der Organismen, 1980
- Insecticidal Benzoylphenyl Ureas: Structure-Activity Relationships as Chitin Synthesis InhibitorsScience, 1978
- A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingAnalytical Biochemistry, 1976