Stereocontrolled construction of substituted pyrrolidines based on intramolecular protodesilylation reaction. Enantiospecific synthesis of (–)-kainic acid and (+)-allokainic acid fromL-serine
- 1 January 1993
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 2,p. 125-127
- https://doi.org/10.1039/c39930000125
Abstract
Novel Stereocontrolled enantiospecific syntheses of (–)-kainic acid and (+)-allokainic acid have been achieved starting from L-serine via two modes of C-2 and C-3 side chain-directed intramolecular protodesilylations of 4-(trimethylsilylmethyl)ethylidenepyrrolidines.Keywords
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