Clinical and pathological study of 24 cases of gliosarcoma

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Abstract
The clinical and pathological features of 24 patients with gliosarcoma were reviewed. The study revealed the following findings. Gliosarcoma occurs more frequently than indicated in the literature, and in this series was present in 8% of all cases of glioblastoma multiforme. The presenting features are not significantly different from those of glioblastoma multiforme. The lesion often presents itself at surgery as a firm, well circumscribed mass within the temporal lobe, and at surgery it is commonly mistaken for a meningioma. There is an increased likelihood of metastases compared to that of glioblastoma. The prognosis is no worse than that of glioblastoma, in spite of the addition of sarcomatous elements.

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