Multiple Coagulative Defects in a Patient with the Waterhouse-Friderichsen Syndrome

Abstract
Afibrino-genemia and other coagulation defects were detected in a fatal case of Waterhouse-Friderischsen syndrome caused by pneumococcus type Xa. The patient, a 17-year-old girl, had had a splenectomy previously for hereditary spherocytosis. The pathogenesis of the abnormalities was unexplained.