Hereditary Defects Affecting Fertility

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Abstract
INVESTIGATION of the literature gives evidence of a more important role for heredity in fertility and fertilization than appears to have been realized. Since both male and female contribute to the fertility level of the biologic unit, a diminished capacity for fertilization of one member will result in lowered fertility of the unit. Some 35 per cent of reproductive failure may be due to factors affecting both members of the unit, and 49 per cent of fertility problems are due to male factors alone.1 , 2 These findings suggest an important involvement of the male gamete in fertility disturbances.In both animals . . .