Goiterogenic Action of Iodide and the Etiology of Goiters in Chicks from Thyroprotein-fed Hens

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Abstract
Summary The goiterogenic action of increased iodide intake is demonstrated both in the normal fowl, follwing continuous treatment, as well as in the developing chick embryo. The goiters in chicks presumably result from large amounts of inorganic iodide deposited in the egg by the hen and are comparable in weight and histology to those observed in chicks from dams fed histology to those observed in chicks from dams fed synthetic thyroprotein. It is suggested that the goiters observed in chicks from dams fed synthetic thyroprotein are caused by the iodide present in thyroprotein.