The Problem of 2′-Protection in Rapid Oligoribonucleotide Synthesis
- 1 January 1987
- journal article
- research article
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 6 (1-2) , 121-129
- https://doi.org/10.1080/07328318708056185
Abstract
An acetal protecting group derived from 1-(2-chloro-4-methylphenyl) piperidin-4-one (12a) has been developed for the blocking of 2′-hydroxy functions in rapid oligoribonucleotide synthesis.Keywords
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