Effect of Raw Soybean Meal and Amino Acids on Pancreatic Hypertrophy in Rats

Abstract
Pancreatic hypertrophy, poor growth and lowered food efficiency result from feeding raw soybean meal to rats as the sole source of dietary protein. Addition of 4 specific amino acids to raw soybean diet corrected the poor growth and reduced the food efficiency but did not prevent the pancreatic hypertrophy. The results support the concept that the decreased growth rate and protein efficiency caused by feeding raw soybean meal are due to direct stimulation of the pancreas which promotes excessive loss of critical amino acids in the pancreatic enzymes excreted in feces.
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