THE ROLE OF MYCOBACTERIUM-XENOPI IN HUMAN-DISEASE

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Abstract
M. xenopi is infrequently recognized as a cause of pulmonary infection. This organism was isolated from 28 patients over a 3-yr period. It was nonpathogenic in 19 and pathogenic in 9. Clinical illness occurred in middle-aged men with other chronic pulmonary diseases. Therapy was associated with clinical improvement but most isolates were resistant to 1st-line antituberculosis drugs. The prevalence of M. xenopi varies geographically but in the province of Ontario [Canada], it is 2nd to M. avium-intracellulare as the most common nontuberculous mycobacterial pathogen.