The Hedamycin Locus Implicates a Novel Aromatic PKS Priming Mechanism

This publication has 46 references indexed in Scilit:

• Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster
  Gene, 2002
• Cloning, Nucleotide Sequence, and Heterologous Expression of the Biosynthetic Gene Cluster for R1128, a Non-steroidal Estrogen Receptor Antagonist
  Journal of Biological Chemistry, 2000
• Pluramycins. Old Drugs Having Modern Friends in Structural Biology
  Accounts of Chemical Research, 1996
• The interaction of hedamycin and DC92-B in a sequence selective manner with DNA in intact human cells
  Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1995
• Hedamycin intercalates the DNA helix and, through carbohydrate-mediated recognition in the minor groove, directs N7-alkylation of guanine in the major groove in a sequence-specific manner
  Chemistry & Biology, 1995
• Comparison of the sequence selectivity of the DNA-alkylating pluramycin antitumour antibiotics DC92-B and hedamycin
  Chemico-Biological Interactions, 1995
• Characterization of the Streptomyces peucetius ATCC 29050 genes encoding doxorubicin polyketide synthase
  Gene, 1994
• Isolation and sequence analysis of polyketide synthase genes from the daunomycin-producing Streptomyces sp. strain C5
  Journal of Bacteriology, 1994
• Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin
  Gene, 1994
• The inhibition of RNA and DNA polymerases by hedamycin
  Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1970