Somatostatin Concentrations in Discrete Hypothalamic Nuclei of Genetically Obese Zucker Rats
- 1 August 1988
- journal article
- research article
- Published by Georg Thieme Verlag KG in Experimental and Clinical Endocrinology & Diabetes
- Vol. 91 (03) , 277-281
- https://doi.org/10.1055/s-0029-1210759
Abstract
Hypothalamic somatostatin concentration was determined in 6.5 to 9 months old male and female genetically obese fatty (fa/fa) and lean (Fa/—) Zucker rats. Similar somatostatin levels were found in fatty and lean animals in the hypothalamic regions previously known to contain the highest hormone levels (median eminence and arcuate, periventicular and ventromedial nuclei). The fatty animals were grossly obese and had a pronounced hyperinsulinemia.Keywords
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