The Antiarrhythmic Action of Ambonestyl (2-Diethylaminoethylisonicotinamide, Mc-4112)
- 2 August 1956
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 255 (5) , 213-216
- https://doi.org/10.1056/nejm195608022550504
Abstract
Ambonestyl was a relatively ineffective agent in the treatment of experimental and human arrhythmias. A comparison with procaine amide showed the latter agent to be definitely superior in the suppression of ventricular arrhythmias. The two drugs have similar rates of metabolism. The induction of premature ventricular contractions by Ambonestyl cautions against its further clinical use.Keywords
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