Mechanisms of insecticide resistance inAedes aegypti(L.) (Diptera: Culicidae) from Puerto Rico

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Abstract
A strain ofAedes aegypti(L.) was collected in Rio Piedras, Puerto Rico, in 1987 and reared through to the F2generation. The strain was shown to be heterozygous for resistance to a range of pyrethroids, but there was no evidence of organophosphate and carbamate resistance. Biochemical studies indicated that the pyrethroid resistance was not metabolically based. Electrophysiological studies at the neuromuscular junction of resistant insects indicated that akdr(nerve insensitivity) type mechanism was operating in this strain. It is not known whether this mechanism was selected by earlier DDT exposure or by the recent ultra-low-volume applications of pyrethroids.