IL-6 protects pancreatic islet beta cells from pro-inflammatory cytokines-induced cell death and functional impairment in vitro and in vivo
- 11 May 2004
- journal article
- Published by Elsevier in Transplant Immunology
- Vol. 13 (1) , 43-53
- https://doi.org/10.1016/j.trim.2004.04.001
Abstract
No abstract availableKeywords
This publication has 36 references indexed in Scilit:
- Cytokine-induced apoptosis and necrosis are preceded by disruption of the mitochondrial membrane potential (Δψm) in pancreatic RINm5F cells: prevention by Bcl-2Molecular and Cellular Endocrinology, 2002
- Interleukin-6 Protects against Fas-mediated Death by Establishing a Critical Level of Anti-apoptotic Hepatic Proteins FLIP, Bcl-2, and Bcl-xLPublished by Elsevier ,2001
- Cytokines Induce Both Necrosis and Apoptosis via a Common Bcl-2-Inhibitable Pathway in Rat Insulin-Producing CellsEndocrinology, 2000
- A20 Inhibits Cytokine-Induced Apoptosis and Nuclear Factor κB–Dependent Gene Activation in IsletsThe Journal of Experimental Medicine, 1999
- Pancreatic β Cell–specific Expression of Thioredoxin, an Antioxidative and Antiapoptotic Protein, Prevents Autoimmune and Streptozotocin-induced DiabetesThe Journal of Experimental Medicine, 1998
- Effect of 15-deoxyspergualin on immediate function and long-term survival of transplanted islets in murine recipients of a marginal islet massDiabetes, 1994
- MTT-assay and neutral red release (NRR)-assay: Relative role in the prediction of the irritancy potential of surfactantsLife Sciences, 1994
- Inhibition of insulin secretion by interleukin‐1β and tumour necrosis factor‐α via an L‐arginine‐dependent nitric oxide generating mechanismFEBS Letters, 1990
- Differential roles of Mac-1+ cells, and CD4+ and CD8+ T lymphocytes in primary nonfunction and classic rejection of islet allografts.The Journal of Experimental Medicine, 1990
- Multiple actions of interleukin 6 within a cytokine networkImmunology Today, 1988