Interleukin-21 enhances T-helper cell type I signaling and interferon-γ production in Crohn’s disease
- 1 March 2005
- journal article
- Published by Elsevier in Gastroenterology
- Vol. 128 (3) , 687-694
- https://doi.org/10.1053/j.gastro.2004.12.042
Abstract
No abstract availableKeywords
This publication has 29 references indexed in Scilit:
- IL-21: a novel IL-2–family lymphokine that modulates B, T, and natural killer cell responsesJournal of Allergy and Clinical Immunology, 2003
- T-bet or Not T-betScience, 2003
- The immunological and genetic basis of inflammatory bowel diseaseNature Reviews Immunology, 2003
- A Critical Role for IL-21 in Regulating Immunoglobulin ProductionScience, 2002
- Interleukin 21 Is a T Helper (Th) Cell 2 Cytokine that Specifically Inhibits the Differentiation of Naive Th Cells into Interferon γ–producing Th1 CellsThe Journal of Experimental Medicine, 2002
- The Common γ Chain (γc) Is a Required Signaling Component of the IL-21 Receptor and Supports IL-21-Induced Cell Proliferation via JAK3Biochemistry, 2002
- IL-21 Limits NK Cell Responses and Promotes Antigen-Specific T Cell ActivationImmunity, 2002
- Interleukin‐15 differentially enhances the expression of interferon‐γ and interleukin‐4 in activated human (CD4+) T lymphocytesImmunology, 1999
- Expanded CD4+CD45RO+ phenotype and defective proliferative response in T lymphocytes from patients with Crohn's diseaseGastroenterology, 1996
- Antibodies to interleukin 12 abrogate established experimental colitis in mice.The Journal of Experimental Medicine, 1995