Transplacental murine cytomegalovirus infection in the brain of SCID mice
Open Access
- 1 January 2007
- journal article
- Published by Springer Nature in Virology Journal
- Vol. 4 (1) , 26
- https://doi.org/10.1186/1743-422x-4-26
Abstract
Congenital cytomegalovirus (CMV) infection is the most common congenital viral infection in humans and the major nonhereditary cause of central nervous system (CNS) developmental disorders. Previous attempts to develop a murine CMV (MCMV) model of natural congenital human CMV (HCMV) infection have failed because MCMV does not cross the placenta in immunocompetent mice.Keywords
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