In Vitro Evaluation of the Effects of Ortho‐, Tripoly‐ and Hexametaphosphate on Zinc, Iron and Calcium Bioavailability

Publisher Website
Google Scholar
Abstract
Effects of orthophosphate, tripolyphosphate and hexametaphosphate on zinc, iron and calcium availability were evaluated following in vitro peptic and peptic‐pancreatic digestions. Solubility was used as an index of potential availability for zinc and calcium; both total soluble and ionized levels were considered for iron. Orthophos‐phate depressed zinc solubility while both polyphosphates enhanced it. All three phosphates depressed ionized, but not total, soluble iron, with the greatest effect exerted by tripolyphosphate. Results indicate that effects of phosphates on zinc and iron availability may be predicted by their effects on soluble zinc and soluble ionic iron levels following in vitro digestions. Effects on calcium availability were not explained by this method.