Mechanisms of invasion and lymphatic penetration in human colorectal cancer
- 1 September 1989
- journal article
- research article
- Published by Springer Nature in Clinical & Experimental Metastasis
- Vol. 7 (5) , 507-516
- https://doi.org/10.1007/bf01753811
Abstract
The invasive areas in 24 unselected human colorectal cancers were examined by light and electron microscopy and it was shown that the invasive process involves tubes of cells rather than single cells, that degenerative changes take place in specialized cells ahead of the invasive cancer cells and that the endothelium of the lymphatic vessels disintegrates, leaving gaps in the endothelial lining.Keywords
This publication has 26 references indexed in Scilit:
- Ultrastructural features of rectal epithelium of the mouse during the early phases of migration to repair a defectVirchows Archiv B Cell Pathology Including Molecular Pathology, 1986
- The nature of host tissue destruction in tumor invasionVirchows Archiv B Cell Pathology Including Molecular Pathology, 1986
- The grading of rectal cancer: historical perspectives and a multivariate analysis of 447 casesHistopathology, 1986
- Lymph node metastasis and cell movement: ultrastructural studies on the rat 13762 mammary carcinoma and Walker carcinomaClinical & Experimental Metastasis, 1985
- Morphology of peritumoral proteoglycan alterations in the rabbit mesentery invaded by V2 carcinoma cellsInternational Journal of Cancer, 1984
- The development of a technique for the morphometric analysis of invasion in cancerJournal of Theoretical Biology, 1984
- The role of cancer cell motility in invasionCancer and Metastasis Reviews, 1984
- The organization of intermediate filaments in normal human colonic epithelium and colonic carcinoma cellsInternational Journal of Cancer, 1983
- Lymphatic metastasisCancer and Metastasis Reviews, 1983
- Group locomotion of PtK1 cellsExperimental Cell Research, 1979