PREPARATION AND PROPERTIES OF THE COFACTOR OF AN ACTH-INACTIVATING ENZYME SYSTEM FROM HUMAN BLOOD1
- 1 October 1961
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 69 (4) , 728-734
- https://doi.org/10.1210/endo-69-4-728
Abstract
The isolation from human blood of a cofactor of an in vitro enzyme system inactivating ACTH is described. The cofactor accelerated the loss of activity of ACTH as measured by the Sayers and Sayers bioassay in the presence of either a blood protein fraction (Cohn III-O) or plasminogen. The ACTH-inactivating activity of the latter in the present system does not appear to be identical with its fibrinolytic action.Keywords
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