The specificity of muscle phosphorylase

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Abstract
The following substances were shown to have no significant inhibitory effect on the synthesis of a polysaccharide from alpha-glucose-1-phosphoric acid with a crystalline muscle phosphorylase prepn. under the exptl. conditions used: D-xylose, D-mannose, D-galactose, D-fructose, L-talose, D-allose, maltose, sucrose, isopropylidene-D-glucose, diisopropylidene-D-glucose, gluconic acid, sorbitol, inositol, ascorbic acid, beta-glucose-1-phosphoric acid and beta-methylglucoside. Under identical exptl. conditions the following substances significantly inhibited the reaction: D-glucose, alpha-methylglucoside and alpha-phenylglucoside. The significance of these results in the elucidation of the specificity of phosphorylase is discussed.