Unusual Bleeding During Pregnancy: Report of a Case Due to Hypoprothrombinemia and Hypoproconvertinemia

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Abstract
A case of transient hypoprothrombinemia and hypoproconvertinemia associated with bleeding and occurring during the eighteenth and nineteenth weeks of a twin pregnancy has been described. The coagulation defect responded to intravenous K1, therapy but not to water soluble K. Death of one fetus and complete infarction of its placenta occurred during the eighteenth week. It is suggested that these events, or their cause, may have adversely influenced liver cell function and precipitated the severe deficiencies of prothrombin and proconvertin.