Improved Treatment of Pancreatic Cancer by IL-12 and B7.1 Costimulation: Antitumor Efficacy and Immunoregulation in a Nonimmunogenic Tumor Model
Open Access
- 30 April 2002
- journal article
- Published by Elsevier in Molecular Therapy
- Vol. 5 (4) , 405-412
- https://doi.org/10.1006/mthe.2002.0570
Abstract
No abstract availableKeywords
This publication has 36 references indexed in Scilit:
- Improved safety through tamoxifen-regulated induction of cytotoxic genes delivered by Ad vectors for cancer gene therapyGene Therapy, 2000
- Adenoviral Gene Transfer of Interleukin 12 into Tumors Synergizes with Adoptive T Cell Therapy Both at the Induction and Effector LevelHuman Gene Therapy, 2000
- Autologous lymphocyte responses to adenovirus-B7-1-transduced human cancer cellsCancer Gene Therapy, 1999
- Interleukin-12 requires initial CD80-mediated T-cell activation to support immune responses toward human breast and ovarian carcinomaCancer Gene Therapy, 1999
- Tumour cell expression of B7 costimulatory molecules and interleukin-12 or granulocyte–macrophage colony-stimulating factor induces a local antitumour response and may generate systemic protective immunityGene Therapy, 1998
- Lack of correlation between rejection of tumor cells co‐expressing interleukin‐2 and B7.1 and vaccine efficiencyEuropean Journal of Immunology, 1997
- Triggering of Natural Killer Cells by the Costimulatory Molecule CD80 (B7-1)Immunity, 1996
- Murine Models of Cancer Cytokine Gene Therapy Using Interleukin‐12aAnnals of the New York Academy of Sciences, 1996
- Active immunotherapy of pancreatic cancer with tumor cells genetically engineered to secrete multiple cytokinesSurgery, 1996
- Tumor-rejection antigens recognized by T lymphocytesCurrent Opinion in Immunology, 1993