The Polyol Domain of Amphidinol 3. A Stereoselective Synthesis of the Entire C(1)−C(30) Sector
- 10 June 2005
- journal article
- research article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 7 (14) , 3111-3114
- https://doi.org/10.1021/ol0511833
Abstract
The richly oxygenated C(1)−C(30) polyol segment of amphidinol 3 has been synthesized in protected form. Incorporated in this long chain are 10 of the 25 stereogenic centers housed in the target. The asymmetric pathway that has been developed is based on the efficient union of three independently prepared subunits.Keywords
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