Prediction of neurological damage after cardiopulmonary bypass surgery

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Abstract
Sixty‐five patients who had coronary artery graft surgery were subjected to detailed neuropsychometric assessment before operation and twice again within 7 days after operation. They were monitored continuously with a cerebral function analysing monitor during the operation. The results of the peroperative cerebral monitoring were compared on completion of the study with the neuropsychometric assessments. Seventy‐six percent of the patients with a significant neuropsychometric deficit after operation also showed significant peroperative changes on the analysing monitor; the majority occurred immediately after the start of perfusion. Twenty‐eight patients failed to demonstrate any evidence of neuropsychometric dejicit and six (21%) of these also showed significant peroperative changes. All patients whose traces demonstrated more than one significant change during the peroperative course had a significant neuropsychometric deficit afterwards.