NUTRITIONAL STATE AND ENDOTOXIN FEVER OF NEWBORN RABBITS

  • 1 January 1979
    • journal article
    • research article
    • Vol. 53  (3) , 279-283
Abstract
At thermoneutral environments, 6-10 day old well-fed rabbits responded to 20 .mu.g/kg i.v. Escherichia coli endotoxin [etox] with biphasic fever: temperature peaks at 60 and 120-150 min and a transient fall between 60 and 90 min after etox injection. In rabbits starved for 24 h and in runt rabbits body temperature did not rise but a decline started 60 min after etox administration, corresponding to the transient fall observed in well-fed animals and continuing until about the 100-120th min; thereafter body temperature tended to stabilize at the low level.