A “One-Pot” Phase Transfer Alkylation/Hydrolysis ofo-Nitrotrifluoroacetanilides. A Convenient Route toN-ALKYLo-Phenylenediamines
- 1 November 1996
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 26 (21) , 4065-4080
- https://doi.org/10.1080/00397919608003827
Abstract
A variety of o-nitrotrifluoroacetanilides undergo a one-pot alkylation/hydrolysis to give N-alkyl o-nitroanilines in 40–94% yield. Dimethylsulfate, benzyl bromide and 1-bromo-propane were used as the electrophiles.Keywords
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