Isolation of Glutamyltaurine from Bovine Brains and Proof of Its ?-Linkage by the B/E Linked Scan SIMS Technique

Abstract
We isolated a glutamyltanurine from bovine brains and determined its structure as .gamma.-glutamyltaurine (.gamma.-Glu-Tau; glutaurine) by use of a new mass spectrometric technique [B/E linked scan sputtered ion mass spectrometry (SIMS)], which we have recently shown to be useful for distinguishing the .gamma.- from the .alpha.-isomer of glutamyldipeptides. Neither the .alpha.-isomer of glutamyltaurine nor any aspartyltaurines could be detected in bovine brain.