The canine copper toxicosis gene MURR1 is not implicated in the pathogenesis of Wilson disease
- 24 July 2006
- journal article
- research article
- Published by Springer Nature in The Esophagus
- Vol. 41 (6) , 582-587
- https://doi.org/10.1007/s00535-006-1807-0
Abstract
It has recently been demonstrated that the Wilson disease (WD) protein directly interacts with the human homolog of the MURR1 protein in vitro and in vivo, and that this interaction is specific for the copper transporter. The aim of the present study was to clarify the role of MURR1 in the pathogenesis of WD as well as in other WD-like disorders of hepatic copper metabolism of unknown origin.Keywords
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