IL-12 plasmid-enhanced DNA vaccination against carcinoembryonic antigen (CEA) studied in immune-gene knockout mice
- 1 September 2000
- journal article
- research article
- Published by Springer Nature in Gene Therapy
- Vol. 7 (18) , 1527-1535
- https://doi.org/10.1038/sj.gt.3301274
Abstract
At the forefront of medicine, Gene Therapy brings you the latest research into genetic and cell-based technologies to treat disease. It also publishes Progress & Prospects reviews and News and Commentary articles, which highlight the cutting edge of the field.Keywords
This publication has 23 references indexed in Scilit:
- Electrically mediated plasmid DNA delivery to hepatocellular carcinomas in vivoGene Therapy, 2000
- Regulation of T-helper-1 versus T-helper-2 activity and enhancement of tumor immunity by combined DNA-based vaccination and nonviral cytokine gene transferGene Therapy, 2000
- Tumor immunity and autoimmunity induced by immunization with homologous DNA.Journal of Clinical Investigation, 1998
- Is IgG2a a good Thl marker in mice?Immunology Today, 1998
- Direct binding of IL-12 to human and murine B lymphocytesInternational Immunology, 1996
- Immunostimulatory DNA Sequences Necessary for Effective Intradermal Gene ImmunizationScience, 1996
- An Improved Plasmid DNA Expression Vector for Direct Injection into Skeletal MuscleHuman Gene Therapy, 1996
- Phase Ia Trial of a Polynucleotide Anti-Tumor Immunization to Human Carcinoembryonic Antigen in Patients with Metastatic Colorectal Cancer. University of Alabama at Birmingham, Birmingham, AlabamaHuman Gene Therapy, 1996
- Adoptive T Cell Therapy of Tumors: Mechanisms Operative in the Recognition and Elimination of Tumor CellsPublished by Elsevier ,1991
- Induction of cytotoxic T-cell responses in vivo in the absence of CD4 helper cellsNature, 1987