Heavy Ion Effects on Yeast Cells: Induction of Canavanine-resistant Mutants
- 1 January 1982
- journal article
- research article
- Published by Taylor & Francis in International Journal of Radiation Biology
- Vol. 42 (6) , 591-600
- https://doi.org/10.1080/09553008214551571
Abstract
The induction of forward mutations (resistance to canavanine) by heavy ion bombardment was investigated in wild type haploid yeast S. cerevisiae. Accelerated ions of Ar, Ti, Ni, Kr, Xe, Pb and U with specific energies between 1.7 and 9.25 MeV/u were obtained from the UNILAC machine at Darmstadt, West Germany. LET[linear energy transfer]-values ranged from 1200 to .apprx. 15,000 keV/.mu.m. There was no unequivocal dependence of mutation induction cross section on either LET or Z*2/.beta.2, but also a prominent influence of ion specific energy. This is explained by the action of long-ranging .delta.-electrons.This publication has 8 references indexed in Scilit:
- Heavy-Ion Effects on Yeast: Survival and Recovery in Vegetative Cells of Different SensitivityRadiation Research, 1982
- Irradiation chamber and sample changer for biological samplesNuclear Instruments and Methods, 1980
- Microdosimetric structure of heavy ion tracks in tissueRadiation and Environmental Biophysics, 1976
- Pathways of ultraviolet mutability in Saccharomyces cerevisiae: I. Some properties of double mutants involving uvs9 and revMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1971
- Range and stopping-power tables for heavy ionsAtomic Data and Nuclear Data Tables, 1970
- Theory of RBE for Heavy Ion Bombardment of Dry Enzymes and VirusesRadiation Research, 1967
- Mutation-Induction and Nuclear Inactivation in Neurospora crassa Using Radiations with Different Rates of Energy LossRadiation Research Supplement, 1967
- Influence of Linear Energy Transfer and Oxygen Tension on the Effectiveness of Ionizing Radiations for Induction of Mutations and Lethality in Saccharomyces cerevisiaeRadiation Research, 1965