2-Trifluoroacetylthiopyridine–1-hydroxybenzotriazole: a powerful reagent for peptide synthesis
- 1 January 1993
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 18,p. 1461-1462
- https://doi.org/10.1039/c39930001461
Abstract
A mixture of trifluoroacetylthiopyridine, the sodium salt of 1-hydroxybenzotriazole, and an acylamino acid is able to acylate amino acid esters in high yields with minimal racemization and should, therefore, be useful for fragment condensation reactions in the liquid phase.Keywords
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