COLORECTAL CARCINOMAS HAVE A CHARACTERISTIC GANGLIOSIDE PATTERN

  • 1 January 1983
    • journal article
    • research article
    • Vol. 61  (1) , 45-48
Abstract
The gangliosides in 6 [human] colorectal and 2 pancreatic carcinomas were examined. Their concentration in the primary tumor and the metastases was 5-10 fold higher than in normal colon mucosa. This increase involved the simple gangliosides, GM3 and GD3, as well as complex mono- and disialogangliosides. Some complex monosialogangliosides were detected in all the colorectal and pancreatic carcinomas but neither in normal colon mucosa and pancreas nor in kidney and lung carcinomas.