STUDIES ON THE FORMIC HYDROGENLYASE SYSTEM OF BACTERIA

Publisher Website
Google Scholar
Abstract
Fermentation of glucose under certain conditions results in formation of a substance required for opt. activity of the formic hydrogenlyase enzyme system. Certain interesting and important strain variations are noted with respect to the effect of glucose on this system. The stimulatory action of hydrolyzed yeast extract on the formic hydrogenlyase system cannot be accounted for by its content of reducing sugar. Results of studies with inhibitors as well as with bacteria grown under different nutritional conditions show that formic hydrogenlyase is a distinct enzyme system and is not dependent on either formic dehydrogenase or hydrogenase activity. Organisms studied were Aerobacter aerogenes (strain D-1), the Crookes, Texas, and biotinless mutant strains of Escherichia coli, and Proteus vulgaris.