Range of viral neutralizing activity and molecular specificity of antibodies induced in cattle by inactivated bovine viral diarrhea virus vaccines
- 1 May 1990
- journal article
- research article
- Published by American Veterinary Medical Association (AVMA) in American Journal of Veterinary Research
- Vol. 51 (5) , 703-707
- https://doi.org/10.2460/ajvr.1990.51.05.703
Abstract
Summary: The range of neutralizing activity to bovine viral diarrhea (bvd) virus and viral protein specificity of antibodies induced by 3 inactivated vaccines were evaluated by use of samples of sera obtained from 13 cattle 14 days after vaccination. Viral neutralizing antibodies were detected in all cattle to each of 10 noncytopathic and 10 cytopathic isolates of bvd virus. A viral-induced polypeptide (53,000 to 56,000 daltons) was detected by radioimmunoprecipitation with serum from all vaccinates. Other viral-induced polypeptides of 115,000, 80,000, 48,000, and 25,000 daltons were precipitated with sera from some vaccinates. Precipitation of those polypeptides was related to the vaccine used. When multiple viral polypeptides were precipitated, the 53,000- to 56,000-dalton polypeptide appeared immunodominant.This publication has 12 references indexed in Scilit:
- VIRAL AND VIRAL PROTEIN SPECIFICITY OF ANTIBODIES INDUCED IN COWS PERSISTENTLY INFECTED WITH NONCYTOPATHIC BOVINE VIRAL DIARRHEA VIRUS AFTER VACCINATION WITH CYTOPATHIC BOVINE VIRAL DIARRHEA VIRUS1988
- Bovine viral diarrhea virus proteins: Heterogeneity of cytopathogenic and non-cytopathogenic strains and evidence of a 53K glycoprotein neutralization epitopeVeterinary Microbiology, 1988
- Monoclonal antibodies with neutralizing activity segregate isolates of bovine viral diarrhea virus into groupsArchiv für die gesamte Virusforschung, 1988
- Neutralizing Monoclonal Antibodies to Bovine Viral Diarrhoea Virus Bind to the 56K to 58K GlycoproteinJournal of General Virology, 1988
- Comparison by the neutralisation assay of pairs of non-cytopathogenic and cytopathogenic strains of bovine virus diarrhoea virus isolated from cases of mucosal diseaseVeterinary Microbiology, 1987
- Variation in the intracellular polypeptide profiles from different isolates of bovine virus diarrhoea virusArchiv für die gesamte Virusforschung, 1987
- SEVERE CLINICAL-DISEASE INDUCED IN CATTLE PERSISTENTLY INFECTED WITH NONCYTOPATHIC BOVINE VIRAL DIARRHEA VIRUS BY SUPERINFECTION WITH CYTOPATHIC BOVINE VIRAL DIARRHEA VIRUS1985
- STUDIES ON TRANS-PLACENTAL TRANSMISSIBILITY OF A BOVINE VIRUS DIARRHEA (BVD) VACCINE VIRUS IN CATTLE .2. INOCULATION OF PREGNANT COWS WITHOUT DETECTABLE NEUTRALIZING ANTIBODIES TO BVD VIRUS 90-229 DAYS BEFORE PARTURITION (51ST TO 190TH DAY OF GESTATION)1984
- FACTORS ASSOCIATED WITH MORBIDITY AND MORTALITY IN FEEDLOT CALVES - THE BRUCE-COUNTY BEEF PROJECT, YEAR 21981
- FACTORS ASSOCIATED WITH MORTALITY IN FEEDLOT CATTLE - BRUCE COUNTY BEEF-CATTLE PROJECT1980